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Wednesday April 28, 2010

Single Gene Is Responsible for OCD-like Behaviors in Mice

Researchers at the Ansary Stem Cell Institute and the Department of Psychiatry at Weill Cornell Medical College discovered that mice missing a single gene developed repetitive obsessive-compulsive-like behaviors.

Other researchers have created mouse models of other types of OCD as recently as 2007. However, for the first time, the findings involving Slitrk5 by Drs. Rafii, Lee and their teams are consistent with imaging studies in humans with OCD that implicate dysregulation of corticostriatal circuitry in the disorder.

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